Best menopause supplement for perimenopause and menopause: the comparison
By the Mush n Go editorial team - 10 November 2026
By the Mush n Go editorial teamPrices checked on 10 November 202611 min read
Comparison
What is the best menopause supplement, and the best supplement for perimenopause? We put Manhaé, Sérélys, Jolly Mama, Nala, Herbalgem, Arkopharma and our own formulas side by side. There is no single winner: most target hot flushes, a few target mood or sleep, only one targets concentration. Here is what each label shows, in a single table, and the right choice for your symptom.
Who is talking: Mush n Go makes Focus, Sleep+ and Anti-Stress, which appear in this comparison. We have no product for hot flushes and do not claim otherwise. This page sets out what each brand shows on its product page and, for our formulas, the technical data sheets from our manufacturer. Information checked on 10 November 2026. We have no ties with the other brands.
Focus
Lion's Mane from the fruiting body, ginkgo, bacopa, saffron and maritime pine, with vitamins B2 and B3. One capsule in the morning.
Discover Focus →
Sleep+
Melatonin 1.9 mg, magnesium bisglycinate, valerian and Reishi from the fruiting body. One capsule in the evening, 30 minutes before bed.
Discover Sleep+ →The best for each criterion
Not a ranking, a choice by symptom.
We make some of the products compared here, so ranking ourselves first would make no sense. Above all, these products don't target the same symptoms. We would rather tell you who stands out on each criterion, with figures to back it up, including when it isn't us, which is the case for hot flushes.
- For hot flushes and sweats, with a stated dose of black cohosh: Nala's Complexe Jour & Nuit, 120 mg a day in total, with sage. Arkofemina contains 3.8 mg, with saffron and ashwagandha; Herbalgem does not state its dose.
- For sage and shatavari: Jolly Mama Péri Support, 123 mg of sage extract and 500 mg of shatavari per two capsules.
- For a formula without plants with hormonal effects: Sérélys Périméno, based on pollen extracts, with 50 mg of saffron, the highest dose in this comparison.
- For oils, omega-3 and vitamins rather than plants: Manhaé Ménopause, one capsule a day, with iron and zinc.
- For the lowest price per day: Manhaé, at €0.27 in a box of 120 from Pharmacie des Drakkars, followed by Arkofemina at €0.48 on a 3-month course.
- For gummies rather than capsules: Nala, two gummies in the morning and two in the evening, sugar-free.
- For your head: brain fog, words that slip away, concentration: Focus by Mush n Go, with Lion's Mane, ginkgo, bacopa, saffron and vitamins B2 and B3. Niacin contributes to normal psychological function. No other formula in this comparison targets concentration.
- For your nights, with no promise on sweats: Sleep+ by Mush n Go, 1.9 mg of melatonin, which contributes to the reduction of time taken to fall asleep, with magnesium, valerian and Reishi. Nala and Sérélys Nuit also provide 1.9 mg of melatonin in the evening.
- To try without risk: Mush n Go, refunded for 60 days, even on opened boxes. Nala advertises a money-back guarantee and free returns for 30 days, with no detailed conditions on its product page; the other brands do not show one.
How we compared
The same criteria for every brand.
We selected the brands on the first page of Google in France for “complément alimentaire ménopause” (menopause supplement) and “complément périménopause” (perimenopause supplement), and those whose names are searched most: Manhaé and Sérélys, each searched more than 5,000 times a month. For each one, we recorded the flagship product on 10 November 2026, from the brand's own product page.
What we compare
The symptom targeted first, the active ingredients and their daily dose, the format and number of doses, the price per day at the recommended dose, and the guarantee.
What we don't compare
How effective it feels: no label can measure that, and every menopause is different. The studies brands cite are often about one ingredient, not about their formula.
Where the prices come from
The brand's online shop on 10 November 2026 for Sérélys, Jolly Mama, Nala, Herbalgem, Arkopharma and Mush n Go. As Manhaé is only sold in pharmacies, we used the price from Pharmacie des Drakkars, an online pharmacy, on the same day.
The details of each check, with sources, are at the bottom of the page. Prices change often, promotions included.
The comparison table
Seven brands, six columns.
One row per product, for one day at the recommended dose. When the brand does not show a piece of information, we say so as it is.
| Product | Targets first | Main active ingredients, per day | How to take | Price per day | Money-back guarantee |
|---|---|---|---|---|---|
| Manhaé Ménopause | General well-being, skin, fatigue | Borage oil 135 mg, fish oil 125 mg (omega-3 90 mg), citrus extract 170 mg, iron 5.7 mg, zinc 5 mg, vitamins B9 and E, beta-carotene | 1 capsule a day, with a meal | €0.27 | Not shown |
| Sérélys Périméno | Hot flushes, sweats, mood | Cytoplasmic pollen extracts 320 mg, saffron extract 50 mg, vitamin E 10 mg | 1 capsule a day | €1.00 | Not shown; “quality and safety guarantee” |
| Jolly Mama Péri Support | Hot flushes, sweats, mood, cycle | Shatavari extract 500 mg, milk thistle extract 250 mg, sage extract 123 mg, saffron extract 30 mg | 2 capsules a day, vegan | €1.13 | Not shown on the product page |
| Nala Complexe Jour & Nuit | Hot flushes, night sweats, sleep | Morning: black cohosh 80 mg, sage 80 mg, B vitamins and vitamin C. Evening: black cohosh 40 mg, sage 50 mg, lemon balm 80 mg, melatonin 1.9 mg, vitamin B6 | 2 gummies in the morning, 2 in the evening | €2.23 | Advertised as 100%, free returns within 30 days, conditions not detailed |
| Herbalgem Gemmocaps Périménopause | Hot flushes, sweating, irritability | Bud macerates of apple tree, grapevine and young raspberry shoots, black cohosh extract: doses not shown | 1 capsule in the morning, 86.6% organic | €0.82 | Not shown |
| Arkopharma Arkofemina Confort Ménopause | Hot flushes, sweats, fatigue, stress, bones | Ashwagandha extract 250 mg, saffron extract 14 mg, cimicifuga extract 3.8 mg, calcium 400 mg, vitamin D3 25 µg | 2 capsules a day, morning and evening | €0.66 | Not shown |
| Mush n Go: Focus, Sleep+, Anti-Stress | Your head and your nights; not hot flushes | Focus: Lion's Mane, ginkgo, bacopa, saffron 14 mg, vitamins B2 and B3. Sleep+: melatonin 1.9 mg, magnesium 60 mg, valerian, Reishi. Anti-Stress: ashwagandha, Reishi, holy basil, schisandra, vitamin B6 | 1 capsule a day per product, vegan | €1.42 | 60 days, even on opened boxes |
Sources: brands' product pages, checked on 10 November 2026; Pharmacie des Drakkars price on the same day for Manhaé. Price per day without subscription or promotion, for the smallest pack size; the best price found is given in the product profiles below. For Mush n Go, price of one product, at one capsule a day.
A figure can't be read on its own. The 250 mg of Lion's Mane extract in Focus corresponds to 1,000 mg of mushroom from the fruiting body, and its 14 mg of saffron is a standardised extract. Always compare an extract with an extract.
Reading the label
Four things to check on a menopause supplement box.
Two “menopause” boxes can target very different symptoms, and contain completely different things. Here is what we looked at, product by product, before filling in the table.
The symptom targeted
Most formulas target hot flushes and sweats first. If your main problem is memory, concentration or falling asleep, check that the formula genuinely addresses it.
The dose of each plant
A clear label gives the daily dose of each extract. Black cohosh ranges here from 3.8 mg to 120 mg a day depending on the brand, and one product page gives no dose at all.
Contraindications
Saffron: several brands advise against it if you take antidepressants. Black cohosh: caution in case of liver disease. Pollen: seek advice if you have allergies. Iron: avoid in case of iron overload.
The price per day
A box can last 21 days or 4 months, at 1, 2 or 4 doses a day. We brought each price back to one day, at the recommended dose.
Product by product
What each product does well, and who it is for.
Each brand has its own logic and its own audience. Here, for each one, is what it targets, who it is for and its key figures.
Manhaé Ménopause
Manhaé Ménopause is for you if you are looking for a plant-free formula based on oils, omega-3, vitamins and minerals, in one capsule a day, at the lowest price per day in this comparison.
Sérélys Périméno
Sérélys Périméno is for you if you want a formula without plants with hormonal effects, based on pollen extracts, with the highest saffron dose in this comparison, 50 mg. The brand also offers Sérélys Méno and a Nuit (night) version, with 1.9 mg of melatonin.
Read our full Sérélys review →
Jolly Mama Péri Support
Jolly Mama Péri Support is for you if you are in perimenopause and looking for a vegan plant-based formula, with 500 mg of shatavari extract and sage, in a glass jar.
Read our full Jolly Mama review →
Nala Complexe Jour & Nuit
Nala's Complexe Jour & Nuit is for you if hot flushes and night sweats are your first concern, if you prefer sugar-free chewable gummies to capsules, and if you want melatonin in the evening.
Herbalgem Gemmocaps Périménopause
Gemmocaps Périménopause is for you if you value gemmotherapy and organic products, with a single capsule in the morning. The dose of each ingredient is not given on the product page.
Arkopharma Arkofemina Confort Ménopause
Arkofemina Confort Ménopause is for you if you want a complete formula sold everywhere, combining plants, calcium and vitamin D3, at under 70 cents a day. Arkopharma also offers single plants: sage, red clover, cimicifuga, soya.
Why Mush n Go
Your head and your nights, not hot flushes.
Our formulas are not “menopause” supplements in the usual sense. They do not act on hot flushes, sweats, hormones or the cycle, and we do not claim they do. They address what many women also describe during perimenopause: brain fog, broken nights, days spent under pressure. If that sounds like you, they can be combined with a formula for hot flushes, or with the treatment prescribed by your doctor, after seeking advice.
- Focus, for your head: Lion's Mane from the fruiting body, 1,000 mg equivalent; ginkgo, bacopa, saffron, maritime pine; vitamins B2 and B3. Riboflavin contributes to normal functioning of the nervous system.
- Sleep+, for falling asleep: 1.9 mg of melatonin, which contributes to the reduction of time taken to fall asleep; 60 mg of magnesium; 100 mg of valerian extract; 130 mg of Reishi extract.
- Anti-Stress, for your days: ashwagandha, Reishi, holy basil and schisandra, with 2 mg of vitamin B6, which contributes to normal psychological function and to the reduction of tiredness and fatigue.
- Brainstoorm, for the morning: our mushroom coffee with 20 mg of caffeine per cup, with Lion's Mane, Cordyceps and Chaga.
- 60-day money-back guarantee, even on opened boxes, and every dose written on the label.
To cover morning, daytime and evening in a single order, our Perimenopause Pack brings together Brainstoorm, Anti-Stress and Sleep+.
To understand these symptoms and what helps day to day, read our guides on menopause brain fog, menopause insomnia and menopause fatigue.
Before you choose
A few precautions that apply to all of them.
Menopause supplements are sold over the counter, but some ingredients call for care, especially if you are on medication.
Before you start
- The products compared here are food supplements: they do not replace a consultation. Troublesome hot flushes, bleeding after 12 months without a period or very heavy periods should be discussed with your GP, your gynaecologist or your midwife.
- Black cohosh, or cimicifuga: rare cases of liver damage have been reported; stop and see a doctor in case of unusual tiredness, dark urine or jaundice.
- Saffron: several brands advise against it if you take antidepressants, including when the antidepressant is prescribed for hot flushes.
- History of breast cancer or hormone-dependent cancer: ask your oncologist's advice before taking any “menopause” supplement.
- Melatonin: not recommended for pregnant or breastfeeding women; seek medical advice in case of epilepsy, asthma or mood disorders; do not drive after taking it.
- Ask your doctor's advice if you take an anticoagulant; Focus is not recommended if you take antidepressants or have epilepsy.
- Sleep+ is not recommended for pregnant or breastfeeding women or for under-18s.
For an overview of this stage of life, from hormone therapy to the habits that help, see our guide menopause and perimenopause.
The Perimenopause Pack
Our answer for your mind and your nights. Brainstoorm in the morning, Anti-Stress during the day, Sleep+ in the evening: all three products together in a 30-day ritual, cheaper than buying them separately, as a one-off purchase or a subscription.
Discover the Perimenopause Pack →Your questions
Everything about choosing a menopause supplement.
What is the best menopause supplement?
There isn't just one: it all depends on your main symptom. For hot flushes with a stated dose of black cohosh, Nala stands out in our comparison; without plants with hormonal effects, Sérélys; at the lowest price, Manhaé or Arkofemina. For concentration and brain fog, Focus by Mush n Go; for falling asleep, Sleep+.
What supplement should I take for perimenopause?
Choose according to what bothers you most. Jolly Mama Péri Support, Sérélys Périméno and Herbalgem Gemmocaps Périménopause are designed for this period and target hot flushes, mood and the cycle first. If your main problem is your head or your nights, Focus and Sleep+ by Mush n Go address them, without promising anything on hot flushes.
Which supplement helps with hot flushes?
In this comparison, Nala, Arkofemina, Herbalgem, Jolly Mama and Sérélys target hot flushes, with black cohosh, sage or pollen extracts. Mush n Go has no product for hot flushes. If they are frequent or wake you up, talk to your doctor: hormone therapy remains the most studied option, and non-hormonal treatments exist.
Manhaé or Sérélys: which should I choose?
They contain completely different things. Manhaé Ménopause combines borage and fish oils, citrus extract, iron, zinc and vitamins, at €0.27 to €0.48 a day depending on the box. Sérélys Périméno is based on pollen extracts and 50 mg of saffron, for €0.90 to €1.00 a day. Sérélys targets hot flushes and mood; Manhaé, more general well-being.
Which supplement helps with sleep during menopause?
For falling asleep, melatonin contributes to the reduction of time taken to fall asleep, an effect obtained with 1 mg taken close to bedtime. Sleep+ by Mush n Go contains 1.9 mg, with magnesium, valerian and Reishi; so do Nala Nuit Paisible and Sérélys Nuit. No melatonin acts on night sweats themselves.
Which supplement helps with memory and concentration during menopause?
Classic menopause formulas don't target concentration. Focus by Mush n Go combines Lion's Mane, ginkgo, bacopa, saffron and vitamins B2 and B3; niacin contributes to normal psychological function. Lion's Mane and saffron have been studied in small trials in women, mostly on mood.
Can you take a menopause supplement with an antidepressant?
Not just any. Jolly Mama, Sérélys Périméno and Arkofemina advise against their product if you take antidepressants, because of the saffron; so does Focus by Mush n Go. Some antidepressants are prescribed for hot flushes: always ask your doctor or pharmacist for advice.
How long should you take a menopause supplement for?
Brands generally recommend at least one to three months: two months minimum for Sérélys, six weeks for Nala. Review things with your doctor if your symptoms don't change, or if they get worse.
How much does a menopause supplement cost per day?
From €0.27 to €2.23 a day in this comparison, at the recommended dose. Manhaé and Arkofemina are the cheapest per day, Nala the most expensive in the small pack size. Mush n Go products work out at €1.42 a day when bought singly and €1.00 with a monthly subscription.
Sources
- Vitavea Santé. “Manhaé Ménopause” product page, vitavea.com. Accessed 10 November 2026.
- Pharmacie des Drakkars. “Manhaé Ménopause, sans hormones” product page: prices of boxes of 30 to 120 capsules. Accessed 10 November 2026.
- Sérélys Pharma. “Sérélys Périméno”, “Sérélys Méno” and “Sérélys Nuit” product pages, serelys.fr. Accessed 10 November 2026.
- Jolly Mama. “Péri Support” product page, jollymama.com. Accessed 10 November 2026.
- Nala pour elle. “Complexe Jour & Nuit” product page, nalapourelle.co. Accessed 10 November 2026.
- HerbalGem. “Complément alimentaire Périménopause” product page, herbalgem.fr. Accessed 10 November 2026.
- Arkopharma. “Arkofemina Confort Ménopause” product page and menopause range page, fr.arkopharma.com. Accessed 10 November 2026.
- European Medicines Agency, Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Cimicifuga racemosa (L.) Nutt., rhizoma.
- Laboratoire FGnutra. “Focus” product technical data sheet, edition of 1 April 2026.
- Laboratoire FGnutra. “Formule sommeil V2” (Sleep+) product technical data sheet, edition of 30 April 2026.
- Laboratoire FGnutra. “Stress V5” (Anti-Stress) product technical data sheet, edition of 12 May 2026.
- Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods (melatonin, riboflavin, niacin, vitamin B6).
The brands mentioned belong to their owners. The information is what each brand publishes; it may have changed since it was checked. Spotted a mistake? Write to us and we will correct it.
Further reading
Before you choose, take the time to identify your main symptom: that is what decides.
Discover our mushroom and adaptogenic plant supplements
Our vegan formulas, made in Toulouse by a French manufacturer.