Sérélys menopause review: ingredients and prices compared
By the Mush n Go editorial team - 10 November 2026
By the Mush n Go editorial teamRecorded on 10 November 202610 min read
Sérélys review
Sérélys is UPSA's pollen-extract menopause range, sold in pharmacies and on serelys.fr: MENO for established menopause, PERIMENO for perimenopause, NUIT for sleep and OSTEO for bones. It's a solid brand, free of hormones and phytoestrogens, that relies on published studies for hot flushes. It also has a formula for nights, Sérélys NUIT, with 1.9 mg of melatonin: exactly the dose in Sleep+, from Mush n Go. What does each capsule contain, how much does a night cost, and what happens if the product doesn't suit you? Here are the labels, line by line.
Who is writing: Mush n Go makes Sleep+, a sleep capsule that competes with Sérélys NUIT, and Anti-Stress, for your days. This page compares what UPSA publishes on serelys.fr and what online pharmacies publish with, for our products, the technical data sheets from our manufacturer. Recorded on 10 November 2026. We have no connection with Sérélys or with UPSA.
Sleep+
Melatonin 1.9 mg, magnesium bisglycinate, valerian and Reishi from the fruiting body. One plant-based capsule, 30 minutes before bedtime.
Try Sleep+ →
Anti-Stress
Ashwagandha, Reishi, holy basil and schisandra, with 2 mg of vitamin B6, which contributes to the reduction of tiredness and fatigue and to normal psychological function.
Discover Anti-Stress →Our verdict in brief
The same dose of melatonin, two ways of thinking about the night.
Sérélys NUIT and Sleep+ share the essentials for falling asleep: 1.9 mg of melatonin per capsule and close to 60 mg of magnesium, in a plant-based capsule made in France. After that, their paths diverge. Sérélys adds 320 mg of pollen extracts and vitamin E, because its range is designed for hot flushes and night sweats. Sleep+ adds valerian and Reishi from the fruiting body, with their content stated, and makes no claim about hot flushes. The real practical difference lies elsewhere: Mush n Go refunds you for 60 days, even on opened boxes; Sérélys only takes back a sealed box.
- Sleep+ is for you if your nights are your main concern: 1.9 mg of melatonin, 60 mg of magnesium, which contributes to a reduction of tiredness and fatigue, valerian and Reishi in a plant-based capsule, a no-commitment subscription at €1.00 per evening, and 60 days to change your mind, even on opened boxes.
- Sérélys is for you if hot flushes and night sweats dominate: MENO and NUIT are based on pollen extracts with no hormones or phytoestrogens, studied against placebo, and the brand presents them as compatible with a history of hormone-dependent cancer, on medical advice.
- On price, Sérélys NUIT costs €1.00 per evening on serelys.fr and €0.75 at Redcare; Sleep+ costs €1.00 per evening on subscription and €1.42 as a one-off purchase.
What is Sérélys?
A pharmacy brand, four menopause formulas built around pollen.
Sérélys was born in Monaco, at Sérélys Pharma, which was bought in October 2024 by UPSA, a French laboratory belonging to the Japanese group Taisho. Its active ingredient is a cytoplasm extract from grass pollens grown in Sweden, stripped of their allergenic outer layer. The brand claims “25 years of expertise” and “5 million users worldwide”. It is sold in pharmacies and directly on serelys.fr.
On the day we recorded it, the range had four menopause-related formulas, all in plant-based capsules at one a day: MENO, the flagship product, PERIMENO with saffron, NUIT with melatonin and magnesium, and OSTEO with vitamins D3, K2 and B6. If you are looking for “Sérélys ONE”: that is the former name of MENO, which replaces it in pharmacies.
The full composition
What is inside a Sérélys capsule.
Sérélys shows short, readable labels: six ingredients for MENO, and the dose of each active ingredient for each formula. Pollen is present throughout, at 320 mg; each formula adds its own complement. The only drawback: the split between the two pollen extracts is not given.
| Per capsule | MENO | PERIMENO | NUIT | OSTEO |
|---|---|---|---|---|
| Pollen extracts | 320 mg (PureCyTonin® PI and GC) | 320 mg (PureCyTonin®) | 320 mg (NoctaCyTonin® SE and TR) | 320 mg (OsteoCyTonin® VH and LM) |
| Vitamin E | 10 mg (83.3%) | 10 mg (83.3%) | 10 mg (83.3%) | 10 mg (83.3%) |
| Saffron | — | 50 mg of stigma extract | — | — |
| Melatonin | — | — | 1.9 mg | — |
| Magnesium | — | — | 56.25 mg (15%) | — |
| Other vitamins | — | — | — | D3 25 µg (500%), K2 180 µg (240%), B6 1.4 mg (100%) |
| Stated target | hot flushes, fatigue | mood, stress, fatigue, hot flushes, sweats | falling asleep, night sweats | bones, heart, hot flushes |
| Price on serelys.fr | 29,90 € (30), 49,90 € (60), 56,95 € (90) | 29,90 € (30) | 29,90 € (30) | 34,00 € (30) |
Source: product pages and FAQ on serelys.fr, recorded on 10 November 2026. The percentages are those of the nutrient reference values displayed. The brand does not give the split between the PI and GC extracts in the 320 mg of MENO. The “Sérélys” tablets still found at some retailers are a Belgian product, unavailable in France on the day of recording.
Hot flushes
Hot flushes are the heart of Sérélys.
On hot flushes, Sérélys has arguments we don't, and we're happy to say so. Its MENO page announces a “natural non-hormonal solution to reduce hot flushes and fatigue”, and the brand cites several studies. The most robust is a double-blind, placebo-controlled trial published in 2005 in the journal Climacteric: 64 menopausal women, three months, with the former tablet form. According to the published abstract, 65% of women in the pollen group had fewer hot flushes, against 38% on placebo.
Another strong point: Sérélys is free of hormones and phytoestrogens, and the brand presents MENO as suitable for women who have had a hormone-dependent cancer, on medical advice. The figures shown on the product page, such as “85.5% of women have fewer hot flushes”, come from a 2015 French study for which the page gives neither the number of participants nor the duration.
Mush n Go sells no supplement for hot flushes or night sweats. Sleep+, Anti-Stress and Focus are not formulated for them, and we claim no effect on them or on hormones. If hot flushes are your main concern, talk to your doctor or pharmacist.
Extract or equivalent
Two figures for the same mushroom: how to read them.
On a supplement label, the same ingredient can appear with two very different weights. Both are correct; they don't measure the same thing. Sérélys contains no mushroom; the question arises here for the Reishi and valerian in Sleep+, for which we give both figures. The same reasoning applies to magnesium: the weight of a magnesium salt is not the weight of the magnesium it provides.
The extract is what's in the capsule
An extract is a concentrate. With a 10:1 ratio, it took 10 g of dried mushroom to obtain 1 g of powder.
The equivalent is the starting weight
“1,000 mg dry equivalent” with a 10:1 ratio means 100 mg of extract in the capsule.
The part of the mushroom matters
The fruiting body is the mushroom itself; the mycelium is its network of filaments. Both are used, and a clear label says which.
The rule for comparing
Always the same column on both sides: extract against extract, equivalent against equivalent. That is what the following table does.
Your nights, line by line
Sleep+ and Sérélys NUIT, line by line.
Both formulas are taken as one capsule, and share the same dose of melatonin. The table compares one capsule of each. For Sleep+, the dried plant equivalent is shown in brackets.
| In the evening | Sleep+ | Sérélys NUIT |
|---|---|---|
| Form | 1 plant-based capsule, 30 minutes before bedtime | 1 plant-based capsule a day |
| Melatonin | 1.9 mg | 1.9 mg |
| Magnesium | 60 mg, 16% of the reference intake, provided by 300 mg of bisglycinate | 56.25 mg, 15%; form not recorded |
| Valerian | 100 mg of extract (600 mg), including 0.4 mg of valerenic acid | absent |
| Reishi | 130 mg of extract (1,950 mg), fruiting body, including 39 mg of polysaccharides | absent |
| Pollen extracts | absent | 320 mg (NoctaCyTonin® SE and TR) |
| Vitamin E | absent | 10 mg, 83.3% |
| Night sweats | no claim | claimed by the brand |
| Vegan | yes | yes |
| Manufacturing | France | France |
Sources: Laboratoire FGnutra technical data sheet for Sleep+ (edition of 30 April 2026); Sérélys NUIT product page on serelys.fr, recorded on 10 November 2026.
For falling asleep, the two capsules are on a par: 1.9 mg of melatonin, almost twice the threshold of 1 mg taken shortly before bedtime from which Europe recognises that melatonin contributes to the reduction of time taken to fall asleep, and a very similar dose of magnesium. Magnesium contributes to a reduction of tiredness and fatigue and to normal functioning of the nervous system. The difference lies in the rest of the formula: Sérélys relies on pollen, for night sweats; Sleep+ relies on valerian and Reishi from the fruiting body, with their content stated. Worth noting: the study Sérélys cites on the NUIT page was carried out with its pollen and vitamin E formula, without melatonin.
Your head and your days
Days on edge, and a head in a fog.
For mood and stress in perimenopause, Sérélys offers PERIMENO: its 320 mg of pollen, plus 50 mg of saffron extract. Anti-Stress, from Mush n Go, is built differently: one capsule combining ashwagandha, Reishi, holy basil and schisandra, with 2 mg of vitamin B6. Vitamin B6 contributes to the reduction of tiredness and fatigue, to normal functioning of the nervous system and to normal psychological function.
| During the day | Anti-Stress | Sérélys PERIMENO |
|---|---|---|
| Form | 1 plant-based capsule a day | 1 plant-based capsule a day |
| Plants | ashwagandha 100 mg of extract (5,000 mg), including 5 mg of withanolides; holy basil 100 mg (400 mg); schisandra 90 mg, including 4.5 mg of schisandrin | saffron 50 mg of stigma extract |
| Mushroom | Reishi 200 mg of extract (3,000 mg), including 90 mg of polysaccharides | absent |
| Vitamins | B6 2 mg, 143% of the reference intake | E 10 mg, 83.3% |
| For hot flushes | nothing | 320 mg of pollen extracts |
| Price for one month | €42.71, or €29.90 on subscription | €29.90 on serelys.fr; €25.79 at Atida |
Sources: Laboratoire FGnutra technical data sheet for Anti-Stress (edition of 12 May 2026); Sérélys PERIMENO product page on serelys.fr and Atida product page, recorded on 10 November 2026.
If it's mainly your concentration that falters, the brain fog so many women talk about in perimenopause, two other Mush n Go products can take over: Focus, a capsule with Lion's Mane, ginkgo, bacopa and saffron, plus vitamins B2 and B3, and Brainstoorm, a mushroom coffee that provides 6 mg of vitamin B5 per cup. Pantothenic acid contributes to normal mental performance and to the reduction of tiredness and fatigue.
Focus
Lion's Mane from the fruiting body, ginkgo, bacopa, saffron and maritime pine, with vitamins B2 and B3, which contribute to normal functioning of the nervous system.
Discover Focus →
Brainstoorm
Lion's Mane, Cordyceps and Chaga in a cup, with 6 mg of vitamin B5, which contributes to normal mental performance.
Discover Brainstoorm →Price, delivery, guarantee
The cost per night, and what the guarantee covers.
Sérélys is sold in pharmacies, where prices are set freely, and directly on serelys.fr. Sleep+ is sold on mushngo.com. One capsule per evening in both cases: the price per evening is our own calculation.
| Prices recorded | Sleep+ | Sérélys NUIT |
|---|---|---|
| Format | 30 capsules, 30 evenings | 30 capsules, 30 evenings |
| 1 box, direct | €42.71, i.e. €1.42 per evening | €29.90, i.e. €1.00 per evening |
| In pharmacies | not sold | €22.59 at Redcare, i.e. €0.75 per evening |
| 3 boxes, direct | €99.86, i.e. €1.11 per evening | €80.73 with the 10% discount, i.e. €0.90 per evening |
| Subscription | €29.90 a month, i.e. €1.00 per evening, no commitment | 5% discount for one product, up to 15% for three, no commitment; discounted price not displayed |
| Delivery | free from €89 | free from €50 according to the terms of sale; free with no minimum on the day of recording |
| Money-back guarantee | 60 days, even on opened boxes, once per customer and per product | no: 14-day withdrawal period, sealed box, return at your own expense |
Prices recorded on 10 November 2026 on mushngo.com, serelys.fr and redcare-pharmacie.fr. The 10% discount for three boxes is the one displayed on serelys.fr; the total is our own calculation. Guarantee conditions taken from each brand's terms and conditions of sale.
On the price of a night, Sérélys NUIT is cheaper in pharmacies, €0.75 against €1.00 for Sleep+ on subscription, and the same price directly on serelys.fr. What you pay extra at Mush n Go as a one-off purchase is a formula with valerian and Reishi, and above all the right to try: if Sleep+ doesn't suit you, we refund you for 60 days, even once opened. At Sérélys, an opened box cannot be returned.
Which one to choose
Pollen for sweats, or the complete formula for falling asleep?
If it's hot flushes and sweats that wake you, Sérélys is a serious brand, hormone-free, studied and sold in pharmacies: talk to your pharmacist. If your nights are falling apart without hot flushes at the forefront, if it's falling asleep and next-day tiredness that weigh on you, Sleep+ was designed for that, with Anti-Stress for your days.
- 1.9 mg of melatonin in one capsule, 30 minutes before bedtime: melatonin contributes to the reduction of time taken to fall asleep.
- 60 mg of magnesium, 16% of the reference intake: it contributes to a reduction of tiredness and fatigue and to normal functioning of the nervous system.
- Valerian and Reishi from the fruiting body, each with its content stated, where Sérélys relies on pollen.
- Anti-Stress for your days: ashwagandha, Reishi, holy basil, schisandra and 2 mg of vitamin B6.
- A no-commitment subscription at €29.90 a month, i.e. €1.00 per evening.
- 60-day money-back guarantee, even on opened boxes: Sérélys only takes back a sealed box.
Sleep+ and Anti-Stress are made in France, like all Mush n Go capsules. Money-back guarantee for 60 days, even on opened boxes.
To cover morning, daytime and evening in a single order, our Perimenopause Pack brings together Brainstoorm, Anti-Stress and Sleep+.
Before you start
- Sérélys advises against its products for pregnant women and children, and recommends asking a pharmacist or doctor if you have a known pollen allergy. For NUIT, as for any melatonin supplement, the brand mentions the risk of drowsiness and precautions in case of epilepsy, asthma, inflammatory or autoimmune disease and mood disorders; PERIMENO is not recommended if you take antidepressants.
- Sleep+ is not recommended for pregnant or breastfeeding women or for under-18s. Melatonin can cause drowsiness: do not drive after taking it. Ask your doctor's advice if you are on medication, particularly anticoagulants, antiepileptics, sedatives or antidepressants.
- Anti-Stress is not recommended in case of thyroid, liver or heart problems or if you take anticoagulant medication; Focus is not recommended if you take antidepressants or have epilepsy. Ask your doctor's advice.
- If you are on menopausal hormone therapy, or on treatment after cancer, talk to your doctor about any food supplement before you start.
- A food supplement should not replace a varied and balanced diet and a healthy lifestyle. Do not exceed the stated daily dose.
The Perimenopause Pack
Our answer for your mind and your nights. Brainstoorm in the morning, Anti-Stress during the day, Sleep+ in the evening: all three products together in a 30-day ritual, cheaper than buying them separately, as a one-off purchase or a subscription.
Discover the Perimenopause Pack →Your questions
Everything about Sérélys for menopause.
What is Sérélys for menopause?
Sérélys is a range of pollen-extract food supplements for menopause, free of hormones and phytoestrogens, published by UPSA. It has four menopause-related formulas: MENO, PERIMENO, NUIT and OSTEO, all in plant-based capsules, one a day. It is sold in pharmacies and on serelys.fr.
What is in Sérélys MENO?
One Sérélys MENO capsule contains 320 mg of cytoplasmic pollen extracts (PureCyTonin® PI and GC) and 10 mg of vitamin E, i.e. 83.3% of the reference values. The full list has six ingredients, including the plant-based HPMC capsule. The split between the two pollen extracts is not displayed.
What is Sérélys ONE?
It's the former name of Sérélys MENO. According to the Vidal database, MENO replaces Sérélys One capsules in boxes of 30 and 60. Some online pharmacies still use the old address or the old text on the MENO product page.
Does Sérélys have side effects?
Sérélys is not intended for pregnant women or children; if you have a known pollen allergy, the brand recommends asking a pharmacist or doctor. Sérélys NUIT, with melatonin, can cause drowsiness and calls for the usual melatonin precautions; PERIMENO, with saffron, is not recommended if you take antidepressants.
Does Sérélys work for hot flushes?
It's the brand's main claim. It relies in particular on a placebo-controlled trial published in 2005: in 64 menopausal women over three months, 65% of women in the pollen group had fewer hot flushes, against 38% on placebo, according to the published abstract. Mush n Go offers no product for hot flushes.
How much does Sérélys for menopause cost?
On 10 November 2026, Sérélys MENO cost €29.90 for 30 capsules, €49.90 for 60 and €56.95 for 90 on serelys.fr. In online pharmacies, the box of 30 cost from €20.69 to €31.39 and the box of 60 from €36.49 to €49.69. Sérélys NUIT cost €29.90 for 30 capsules direct and €22.59 at Redcare.
Where can I buy Sérélys? Is it sold in pharmacies?
Yes, Sérélys is sold in pharmacies and parapharmacies, both in-store and online (Redcare, Citypharma, Atida, Pharmashopi), and directly on serelys.fr, with an optional subscription.
What do reviews say about Sérélys?
On 10 November 2026, Sérélys MENO in the box of 60 displayed 4.5 out of 5 from 244 reviews at Atida and 4.6 out of 5 from 52 reviews at Redcare. The brand's own site does not display reviews.
Sérélys NUIT or Sleep+: which one to choose?
Both provide 1.9 mg of melatonin and around 60 mg of magnesium per capsule. Sérélys NUIT adds 320 mg of pollen and vitamin E, for night sweats. Sleep+ adds valerian and Reishi, and is refundable for 60 days, even on opened boxes. If night sweats wake you, Sérélys NUIT targets them; if it's falling asleep, both are suitable.
Is Sérélys reimbursed, or does it come with a money-back guarantee?
No. Sérélys is a food supplement, not reimbursed by the French national health insurance (Assurance maladie), and serelys.fr does not offer a money-back guarantee: only the 14-day withdrawal period, for an unsealed product. Mush n Go refunds Sleep+ for 60 days, even on opened boxes.
Sources
- UPSA. Sérélys MENO, PERIMENO, NUIT and OSTEO product pages, Expertise, Technology, Studies and Subscription pages, FAQ, legal notice and terms and conditions of sale, serelys.fr. Accessed on 10 November 2026.
- Vidal. Parapharmacy entry “Sérélys MENO gélules”, vidal.fr. Accessed on 10 November 2026.
- Redcare Pharmacie, Pharmacie Citypharma, Atida and Pharmashopi. Sérélys product pages. Accessed on 10 November 2026.
- Winther K, Rein E, Hedman C. Femal, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climacteric, 2005, 8(2):162-170.
- Fait T, Sailer M, Regidor PA. Prospective observational study to evaluate the efficacy and safety of the pollen extract Sérélys® in the management of women with menopausal symptoms. Gynecological Endocrinology, 2019, 35(4):360-363.
- Annuaire des entreprises (French business directory, recherche-entreprises.api.gouv.fr). UPSA SAS entry, SIREN 803 247 956. Accessed on 10 November 2026.
- Mush n Go. Sleep+, Anti-Stress and Focus product pages, refund policy, mushngo.com. Accessed on 10 November 2026.
- Laboratoire FGnutra. Product technical data sheet “Formule sommeil V2” (Sleep+), edition of 30 April 2026.
- Laboratoire FGnutra. Product technical data sheet “Stress V5” (Anti-Stress), edition of 12 May 2026.
- Laboratoire FGnutra. Product technical data sheet “Focus”, edition of 1 April 2026.
- Laboratoire FGnutra. Product technical data sheet “Brainstoorm Café 180 g”, edition of 28 January 2026.
- Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods (melatonin, magnesium, vitamins B2, B3, B5 and B6).
Sérélys, PureCyTonin, NoctaCyTonin and UPSA are trademarks of their owner. The information about these products is what the brand and its retailers publish; it may have changed since it was recorded. Spotted a mistake? Write to us and we will correct it.
Further reading
Perimenopause plays out on several fronts. Here are our other guides and comparisons, so you can choose with full knowledge.
Discover our mushroom and adaptogenic plant supplements
Our vegan formulas, made in Toulouse by a French manufacturer.