Immunity

An adaptogenic or medicinal mushroom is a mushroom that, thanks to its composition, acts positively on the body. These superfoods have been used for centuries in Chinese medicine. Thanks to their active ingredients, they are able to regulate the body, control our body's responses to stress, strengthen immunity, concentration and energy, improve sleep or promote muscular well-being.

No, Mush n Go adaptogenic mushrooms are only beneficial for the body and do not create any psychotropic effects. They are completely different from hallucinogenic mushrooms and do not contain any hallucinogenic substances such as psilocybin, which is responsible for the hallucinogenic effects. In addition, our products are legal worldwide.

There are several categories of mushrooms:

Gastronomic mushrooms, which we know well, such as button mushrooms or porcini mushrooms.
Medicinal mushrooms such as Chaga, Cordyceps, Lion's Mane or Reishi.
Hallucinogenic mushrooms, which contain substances like psilocybin, which alter the brain.
These categories of mushrooms are quite distinct and have nothing to do with each other. With Mush n Go formulas, we offer you products made exclusively from medicinal mushrooms, known for their health benefits without any harmful effects.

It all depends on each person's body and metabolism. Some people will see results after the first few days of treatment (some even during the first intake) while others will see them after a few weeks.
If necessary, you can increase your daily dose.

Yes. These mushrooms are called “adaptogens” and have several common active ingredients called polysaccharides. Thus, by consuming several cures at the same time, a synergistic effect will be created to combine all the good effects.

Yes, adaptogenic mushrooms are legal in France, as long as they are marketed in accordance with current regulations regarding dietary supplements or natural products. However, it is important to note that regulations may vary depending on how the products are marketed and the health claims associated with them.

Our formulas are declared and validated by the DGCCRF via the regulation of food supplements. Please note that this is not necessarily the case for all adaptogenic mushrooms that you find on the Internet. It is recommended to check the regulations in force and to obtain products from reputable and reliable suppliers to guarantee their quality and compliance.

You can find the analyses of our mushrooms here:

• DGCCRF certificate
• The Analyses

Yes, there are hundreds of studies on adaptogenic mushrooms that prove their effectiveness. Here is some of the research on our mushrooms

Lion's mane (Hericium Ericanus)

1. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment
* This study showed that Lion's Mane improves cognitive impairment in patients, showing significant beneficial effects on memory and cognition.
* Source: https://pubmed.ncbi.nlm.nih.gov/18844328/

* Study title: Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacins
* Lay summary: This study examines how the mushroom Hericium erinaceus, enriched with erinacines (a type of bioactive compound), can protect the brain. The researchers found that this mushroom extract can help protect neurons, support neuronal growth, and potentially prevent neurodegenerative diseases.

https://pubmed.ncbi.nlm.nih.gov/29951133/

The Neuroprotective Properties of Hericium erinaceus (Lion's Mane) in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model
* The study found that Lion's Mane protects neurons from damage, improving cognitive health in a mouse model of Alzheimer's disease.


https://pubmed.ncbi.nlm.nih.gov/27809277


Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice
* This study demonstrates that Lion's Mane supplementation increases hippocampal neurotransmission and recognition memory in animals

https://pubmed.ncbi.nlm.nih.gov/28115973/

Reishi (Ganoderma lucidum)

Neuroprotective effects of ganoderma lucidum (Reishi) polysaccharides against oxidative stress-induced neuronal apoptosis
* Reishi polysaccharides have shown neuroprotective effects by protecting neurons against stress-induced apoptosis
https://pubmed.ncbi.nlm.nih.gov/28761429/

1. Evaluation of Antianxiety Potential of Four Ganoderma (Reishi) Species from India in Mice
* This study showed that different species of Reishi possess significant anti-anxiety potential, reducing anxiety in mice.
*
* https://pubmed.ncbi.nlm.nih.gov/28008811/


Safety and Efficacy of Ganoderma lucidum (Lingzhi) and San Miao San Supplementation in Patients With Rheumatoid Arthritis: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial
* This study demonstrated that Reishi is safe and effective in reducing inflammation and improving symptoms in patients with rheumatoid arthritis, contributing to better sleep quality through reduced pain and discomfort.

https://pubmed.ncbi.nlm.nih.gov/17907228/

Effect of Ganoderma lucidum on Time to Fall Asleep

* Reishi extract has been studied for its effects on reducing the time to fall asleep and increasing the total sleep time. The results show that Reishi has hypnotic effects similar to benzodiazepines and can potentiate phenobarbital-induced sleep.


https://www.sciencedirect.com/science/article/abs/pii/S0378874111008981#:~:text=Its%20%E2%80%9CAn%2DShen%E2%80%9D%20effect,with%20neurasthenia%20and%20mental%20confusion

Cordyceps:
1. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II
* This study explores the beneficial effects of Cordyceps sinensis, a valuable ancient Chinese herb, on human health.
*https://pubmed.ncbi.nlm.nih.gov/9884180/

Effects of Cordyceps sinensis supplementation during 12 weeks in amateur marathoners: A randomized, double-blind placebo-controlled trial
* This study demonstrated that supplementing with Cordyceps sinensis for 12 weeks improves the performance of amateur marathon runners.



https://www.sciencedirect.com/science/article/abs/pii/S2210803322000392

3. Chen, Steve et al. (2010)
Study title: Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial
Abstract: Study on the improvement of physical performance by Cs-4 in healthy elderly subjects.

https://pubmed.ncbi.nlm.nih.gov/20804368/


1. Functional study of Cordyceps sinensis and cordycepin in male reproduction: A review
* This review explores the beneficial effects of Cordyceps sinensis and cordycepin on male reproduction, showing significant improvement in reproductive parameters.
*https://pubmed.ncbi.nlm.nih.gov/28911537/

Lion's mane hericium ericanus
1. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment
* This study showed that Lion's Mane improves cognitive impairment in patients, showing significant beneficial effects on memory and cognition.
* Source: https://pubmed.ncbi.nlm.nih.gov/18844328/


The Neuroprotective Properties of Hericium erinaceus (Lion's Mane) in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model
* The study found that Lion's Mane protects neurons from damage, improving cognitive health in a mouse model of Alzheimer's disease.


https://pubmed.ncbi.nlm.nih.gov/27809277/


Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice
* This study demonstrates that Lion's Mane supplementation increases hippocampal neurotransmission and recognition memory in animals

https://pubmed.ncbi.nlm.nih.gov/28115973/



Chaga (Inonotus obliquus)
1. Review on Chaga Medicinal Mushroom, Inonotus obliquus (Higher Basidiomycetes): Realm of Medicinal Applications and Approaches on Estimating its Resource Potential
* This review examines the medicinal applications of Chaga mushroom and approaches to assess its potential as a resource.
* Source https://pubmed.ncbi.nlm.nih.gov/25746615/

1. Immunostimulating Activity by Polysaccharides Isolated from Fruiting Body of Inonotus obliquus (Chaga)
* Isolated Chaga polysaccharides have shown significant immunostimulatory activity, strengthening the immune system.
*Source: https://link.springer.com/article/10.1007/s10059-011-0022-x

Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus (Chaga)
* This study showed that Chaga polysaccharides have notable anticancer effects, inhibiting the growth of cancer cells.
https://www.sciencedirect.com/science/article/pii/S2225411020309809

Oyster Mushroom (Pleurotus ostreatus)
1. Antioxidant and Anti-Inflammatory Activity of Five Medicinal Mushrooms of the Genus Pleurotus
* Studies show that Oyster mushroom has significant anti-inflammatory and antioxidant properties
https://pubmed.ncbi.nlm.nih.gov/36009288/

Pharmacological activities of Oyster mushroom (Pleurotus ostreatus)
* This research highlighted the cholesterol-lowering and antioxidant effects of Pleurotus ostreatus, demonstrating its potential to improve cardiovascular health and reduce cholesterol levels.


https://www.sciencedirect.com/science/article/pii/S2772566923000460#:~:text=Pharmacological%20research%20shows%20that%20P,%2Dbacterial%20and%20anti%2Dinflammatory

Turkey Tail (Trametes versicolor)
1. Effects of polysaccharopeptide (PSP) from Trametes versicolor on the immune response in cancer patients
* The study demonstrated that polysaccharopeptide (PSP) extracted from Turkey Tail stimulates the immune response in cancer patients, improving their quality of life and resistance to infections.
https://www.sciencedirect.com/science/article/abs/pii/S1877117319300353#:~:text=PSP%20activates%20and%20enhances%20the,stimulates%20the%20filtration%20of%20both

Immunomodulatory and Antitumor Activities of Polysaccaropeptide from Trametes versicolor
* This study highlighted the immunomodulatory and antitumor activities of PSP, suggesting its potential as a therapeutic adjunct in anticancer treatments.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592279/

Maitake (Grifola frondosa)
1. Bioactive Ingredients and Medicinal Values ​​of Grifola frondosa (Maitake)
* This study provides a comprehensive overview of the bioactive constituents of Maitake and their potential health benefits. Polysaccharides, especially β-glucans, have shown significant antitumor and immunomodulatory activities. Maitake also contains proteins, glycoproteins, and small organic molecules that possess diverse bioactivities.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824844/#:~:text=frondosa%20is%20composed%20of%20proteins,and%20have%20shown%20various%20bioactivities

About mushrooms in general
10. Powell, Martin (2013)
Book Title: Medicinal Mushrooms: the Essential Guide
Summary: Essential guide to medicinal mushrooms, their therapeutic properties and practical applications.
Source: Powell, M. (2013). Medicinal Mushrooms: the Essential Guide. Mycology Press.
11. Benzie, Iris F. & Wachtel-Galor, Sissi (2011)
Book title: Herbal Medicine: Biomolecular and Clinical Aspects
Abstract: Exploration of the biomolecular and clinical aspects of medicinal plants, including medicinal mushrooms.
Source: Benzie, IF, & Wachtel-Galor, S. (Eds.). (2011). Herbal Medicine: Biomolecular and Clinical Aspects (2nd ed.). CRC Press/Taylor & Francis. Available at: NCBI Bookshelf.

There are hundreds of other studies on adaptogenic mushrooms that demonstrate their many health benefits. Feel free to do your own research, which may only encourage you to incorporate mushrooms into your daily routine.